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Visualizing DNA folding and RNA in embryos at single-cell resolution
Establishment of cell types during development requires precise interactions between genes and distal regulatory sequences. Our understanding of how these interactions look in three dimensions, vary across cell types in complex tissue, and relate to transcription remains limited. Here we describe op...
Autores principales: | Mateo, Leslie J., Murphy, Sedona E., Hafner, Antonina, Cinquini, Isaac S., Walker, Carly A., Boettiger, Alistair N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6556380/ https://www.ncbi.nlm.nih.gov/pubmed/30886393 http://dx.doi.org/10.1038/s41586-019-1035-4 |
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