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Visualizing DNA folding and RNA in embryos at single-cell resolution

Establishment of cell types during development requires precise interactions between genes and distal regulatory sequences. Our understanding of how these interactions look in three dimensions, vary across cell types in complex tissue, and relate to transcription remains limited. Here we describe op...

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Detalles Bibliográficos
Autores principales: Mateo, Leslie J., Murphy, Sedona E., Hafner, Antonina, Cinquini, Isaac S., Walker, Carly A., Boettiger, Alistair N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6556380/
https://www.ncbi.nlm.nih.gov/pubmed/30886393
http://dx.doi.org/10.1038/s41586-019-1035-4