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Deep learning connects DNA traces to transcription to reveal predictive features beyond enhancer–promoter contact
Chromatin architecture plays an important role in gene regulation. Recent advances in super-resolution microscopy have made it possible to measure chromatin 3D structure and transcription in thousands of single cells. However, leveraging these complex data sets with a computationally unbiased method...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8187657/ https://www.ncbi.nlm.nih.gov/pubmed/34103507 http://dx.doi.org/10.1038/s41467-021-23831-4 |