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Celecoxib, indomethacin, and ibuprofen prevent 6-hydroxydopamine-induced PC12 cell death through the inhibition of NFκB and SAPK/JNK pathways

OBJECTIVE(S): The possible action of nonsteroidal anti-inflammatory drugs (NSAIDs) in the reduction of reactive oxygen species (ROS) and also as anti-apoptotic agents may suggest them as putative agents for the treatment of neurodegenerative diseases. This study was designed to explore some pathways...

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Detalles Bibliográficos
Autores principales: Ramazani, Elham, Tayarani-Najaran, Zahra, Fereidoni, Masoud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6556502/
https://www.ncbi.nlm.nih.gov/pubmed/31217926
http://dx.doi.org/10.22038/IJBMS.2019.34011.8091