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Reproduction and longevity: A Mendelian randomization study of gonadotropin-releasing hormone and ischemic heart disease

BACKGROUND: According to well-established evolutionary biology theory there is a trade-off between reproduction and longevity, implying that upregulating the reproductive axis might drive major diseases. We assessed whether the central driver of reproduction gonadotropin-releasing hormone 1 (GnRH1)...

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Detalles Bibliográficos
Autores principales: Schooling, C.M., Ng, Jack C.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6556548/
https://www.ncbi.nlm.nih.gov/pubmed/31198836
http://dx.doi.org/10.1016/j.ssmph.2019.100411