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Protein and Glycan Mimicry in HIV Vaccine Design

Antigenic mimicry is a fundamental tenet of structure-based vaccinology. Vaccine strategies for the human immunodeficiency virus type 1 (HIV-1) focus on the mimicry of its envelope spike (Env) due to its exposed location on the viral membrane and role in mediating infection. However, the virus has e...

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Detalles Bibliográficos
Autores principales: Seabright, Gemma E., Doores, Katie J., Burton, Dennis R., Crispin, Max
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6556556/
https://www.ncbi.nlm.nih.gov/pubmed/31028779
http://dx.doi.org/10.1016/j.jmb.2019.04.016