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IL-17A Increases Multiple Myeloma Cell Viability by Positively Regulating Syk Expression
PURPOSE: Elevated IL-17 produced by T(h)17 cells was reported to promote myeloma cell growth and inhibit immune function in multiple myeloma (MM). IL-17A was also reported to promote MM growth through IL-17 receptors and enhance adhesion to bone marrow stromal cells (BMSCs). Spleen tyrosine kinase (...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Neoplasia Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6556560/ https://www.ncbi.nlm.nih.gov/pubmed/31174059 http://dx.doi.org/10.1016/j.tranon.2019.04.023 |