IL-17A Increases Multiple Myeloma Cell Viability by Positively Regulating Syk Expression

PURPOSE: Elevated IL-17 produced by T(h)17 cells was reported to promote myeloma cell growth and inhibit immune function in multiple myeloma (MM). IL-17A was also reported to promote MM growth through IL-17 receptors and enhance adhesion to bone marrow stromal cells (BMSCs). Spleen tyrosine kinase (...

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Detalles Bibliográficos
Autores principales: Wang, Shunye, Ma, Yanan, Wang, Xudong, Jiang, Jie, Zhang, Chenglu, Wang, Xinfeng, Jiang, Yijing, Huang, Hongming, Hong, Liu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2019
Materias:
Original article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6556560/
https://www.ncbi.nlm.nih.gov/pubmed/31174059
http://dx.doi.org/10.1016/j.tranon.2019.04.023

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