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Revising the structure of a new eicosanoid from human platelets to 8,9–11,12-diepoxy-13-hydroxyeicosadienoic acid

Eicosanoids are critical mediators of fever, pain, and inflammation generated by immune and tissue cells. We recently described a new bioactive eicosanoid generated by cyclooxygenase-1 (COX-1) turnover during platelet activation that can stimulate human neutrophil integrin expression. On the basis o...

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Detalles Bibliográficos
Autores principales: Kornilov, Andrei, Kennedy, Paul D., Aldrovandi, Maceler, Watson, Andrew J. A., Hinz, Christine, Harless, Bryan, Colombo, Joseph, Maxey, Kirk M., Tyrrell, Victoria J., Simon, Matthew, Aggarwal, Varinder K., Boeglin, William E., Brash, Alan R., Murphy, Robert C., O'Donnell, Valerie B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6556573/
https://www.ncbi.nlm.nih.gov/pubmed/31061099
http://dx.doi.org/10.1074/jbc.RA119.008915