Cargando…
Pharmacokinetics of the SABRE agent 4,6-d(2)-nicotinamide and also nicotinamide in rats following oral and intravenous administration
To prepare the way for using the isotopically labelled SABRE hyperpolarized 4,6-d(2)-nicotinamide as an MRI agent in humans we have performed an in-vivo study to measure its pharmacokinetics in the plasma of healthy rats after intravenous and oral administration. Male Han Wistar rats were dosed with...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier Science B.V
2019
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6556870/ https://www.ncbi.nlm.nih.gov/pubmed/31077749 http://dx.doi.org/10.1016/j.ejps.2019.05.004 |