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Cell-Type Heterogeneity in Adipose Tissue Is Associated with Complex Traits and Reveals Disease-Relevant Cell-Specific eQTLs

Adipose tissue is an important endocrine organ with a role in many cardiometabolic diseases. It is comprised of a heterogeneous collection of cell types that can differentially impact disease phenotypes. Cellular heterogeneity can also confound -omic analyses but is rarely taken into account in anal...

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Detalles Bibliográficos
Autores principales: Glastonbury, Craig A., Couto Alves, Alexessander, El-Sayed Moustafa, Julia S., Small, Kerrin S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6556877/
https://www.ncbi.nlm.nih.gov/pubmed/31130283
http://dx.doi.org/10.1016/j.ajhg.2019.03.025