Cargando…

Neutrophil extracellular trap induced by HMGB1 exacerbates damages in the ischemic brain

It has been reported that neutrophil extracellular traps (NETs) play important roles in non-infectious diseases. In ischemic stroke, neutrophils infiltrate damaged brain tissue soon after injury and aggravate inflammation. Using a rat permanent MCAO model, we showed citrullinated histone H3(+) (CitH...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Seung-Woo, Lee, Hahnbie, Lee, Hye-Kyung, Kim, Il-Doo, Lee, Ja-Kyeong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6556959/
https://www.ncbi.nlm.nih.gov/pubmed/31177989
http://dx.doi.org/10.1186/s40478-019-0747-x