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An improved Tet-on system in microRNA overexpression and CRISPR/Cas9-mediated gene editing
BACKGROUND: Tetracycline (Tet)-regulated expression system has become a widely applied tool to control gene activity. This study aimed to improve the Tet-on system with superior regulatory characteristics. RESULTS: By comprehensively comparing factors of transactivators, Tet-responsive elements (TRE...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6556963/ https://www.ncbi.nlm.nih.gov/pubmed/31198556 http://dx.doi.org/10.1186/s40104-019-0354-5 |