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Pan-cancer analysis identifies telomerase-associated signatures and cancer subtypes

BACKGROUND: Cancer cells become immortalized through telomere maintenance mechanisms, such as telomerase reverse transcriptase (TERT) activation. In addition to maintaining telomere length, TERT activates manifold cell survival signaling pathways. However, telomerase-associated gene signatures in ca...

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Detalles Bibliográficos
Autores principales: Luo, Zhenhua, Wang, Weixu, Li, Feng, Songyang, Zhou, Feng, Xuyang, Xin, Changchang, Dai, Zhiming, Xiong, Yuanyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6556968/
https://www.ncbi.nlm.nih.gov/pubmed/31179925
http://dx.doi.org/10.1186/s12943-019-1035-x