Downregulation of lncRNA CCDC26 contributes to imatinib resistance in human gastrointestinal stromal tumors through IGF-1R upregulation

Imatinib is the first line of therapy for patients with metastatic or gastrointestinal stromal tumors (GIST). However, drug resistance limits the long-term effect of imatinib. Long non-coding RNAs (lncRNAs) are emerging as key players in regulating drug resistance in cancer. In this study, we invest...

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Detalles Bibliográficos
Autores principales: Yan, Jingyi, Chen, Didi, Chen, Xiaolei, Sun, Xuecheng, Dong, Qiantong, Hu, Changyuan, Zhou, Feng, Chen, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação Brasileira de Divulgação Científica 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6556970/
https://www.ncbi.nlm.nih.gov/pubmed/31166382
http://dx.doi.org/10.1590/1414-431X20198399

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6556970/
https://www.ncbi.nlm.nih.gov/pubmed/31166382
http://dx.doi.org/10.1590/1414-431X20198399

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