CCNE1 Amplification and Centrosome Number Abnormality in Serous Tubal Intraepithelial Carcinoma- Further Evidence Supporting its Role as a Precursor of Ovarian High-Grade Serous Carcinoma

Aberration in chromosomal structure characterizes almost all cancers and has profound biological significance in tumor development. It can be facilitated by various mechanisms including overexpression of cyclin E1 and centrosome amplification. Since ovarian high-grade serous carcinoma has pronounced...

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Detalles Bibliográficos
Autores principales: Kuhn, Elisabetta, Wang, Tian-Li, Doberstein, Kai, Bahadirli-Talbott, Asli, Ayhan, Ayse, Sehdev, Ann Smith, Drapkin, Ronny, Kurman, Robert J., Shih, Ie-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6557162/
https://www.ncbi.nlm.nih.gov/pubmed/27443516
http://dx.doi.org/10.1038/modpathol.2016.101

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6557162/
https://www.ncbi.nlm.nih.gov/pubmed/27443516
http://dx.doi.org/10.1038/modpathol.2016.101

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