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Engineered bacteriophages for treatment of a patient with a disseminated drug resistant Mycobacterium abscessus
A 15-year-old cystic fibrosis patient with a disseminated Mycobacterium abscessus infection was treated with a three-phage cocktail following bilateral lung transplantation. Effective lytic phage derivatives that efficiently kill the infectious M. abscessus strain were developed by genome engineerin...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6557439/ https://www.ncbi.nlm.nih.gov/pubmed/31068712 http://dx.doi.org/10.1038/s41591-019-0437-z |