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High extracellular lactate causes reductive carboxylation in breast tissue cell lines grown under normoxic conditions
In cancer tumors, lactate accumulation was initially attributed to high glucose consumption associated with the Warburg Effect. Now it is evident that lactate can also serve as an energy source in cancer cell metabolism. Additionally, lactate has been shown to promote metastasis, generate gene expre...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6557470/ https://www.ncbi.nlm.nih.gov/pubmed/31181081 http://dx.doi.org/10.1371/journal.pone.0213419 |