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Comparative analyses of sperm DNA methylomes among human, mouse and cattle provide insights into epigenomic evolution and complex traits

Sperm DNA methylation is crucial for fertility and viability of offspring but epigenome evolution in mammals is largely understudied. By comparing sperm DNA methylomes and large-scale genome-wide association study (GWAS) signals between human and cattle, we aimed to examine the DNA methylome evoluti...

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Detalles Bibliográficos
Autores principales: Fang, Lingzhao, Zhou, Yang, Liu, Shuli, Jiang, Jicai, Bickhart, Derek M., Null, Daniel J., Li, Bingjie, Schroeder, Steven G., Rosen, Benjamin D., Cole, John B., Van Tassell, Curtis P., Ma, Li, Liu, George E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6557555/
https://www.ncbi.nlm.nih.gov/pubmed/30810461
http://dx.doi.org/10.1080/15592294.2019.1582217