Cargando…
Comparative analyses of sperm DNA methylomes among human, mouse and cattle provide insights into epigenomic evolution and complex traits
Sperm DNA methylation is crucial for fertility and viability of offspring but epigenome evolution in mammals is largely understudied. By comparing sperm DNA methylomes and large-scale genome-wide association study (GWAS) signals between human and cattle, we aimed to examine the DNA methylome evoluti...
Autores principales: | Fang, Lingzhao, Zhou, Yang, Liu, Shuli, Jiang, Jicai, Bickhart, Derek M., Null, Daniel J., Li, Bingjie, Schroeder, Steven G., Rosen, Benjamin D., Cole, John B., Van Tassell, Curtis P., Ma, Li, Liu, George E. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6557555/ https://www.ncbi.nlm.nih.gov/pubmed/30810461 http://dx.doi.org/10.1080/15592294.2019.1582217 |
Ejemplares similares
-
Integrating Signals from Sperm Methylome Analysis and Genome-Wide Association Study for a Better Understanding of Male Fertility in Cattle
por: Fang, Lingzhao, et al.
Publicado: (2019) -
Comprehensive analyses of 723 transcriptomes enhance genetic and biological interpretations for complex traits in cattle
por: Fang, Lingzhao, et al.
Publicado: (2020) -
Epigenomics and genotype-phenotype association analyses reveal conserved genetic architecture of complex traits in cattle and human
por: Liu, Shuli, et al.
Publicado: (2020) -
Comparative whole genome DNA methylation profiling of cattle sperm and somatic tissues reveals striking hypomethylated patterns in sperm
por: Zhou, Yang, et al.
Publicado: (2018) -
Identification of a Nonsense Mutation in CWC15 Associated with Decreased Reproductive Efficiency in Jersey Cattle
por: Sonstegard, Tad S., et al.
Publicado: (2013)