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Identification of DNA methylation patterns predisposing for an efficient response to BCG vaccination in healthy BCG-naïve subjects

The protection against tuberculosis induced by the Bacille Calmette Guérin (BCG) vaccine is unpredictable. In our previous study, altered DNA methylation pattern in peripheral blood mononuclear cells (PBMCs) in response to BCG was observed in a subgroup of individuals, whose macrophages killed mycob...

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Detalles Bibliográficos
Autores principales: Das, Jyotirmoy, Verma, Deepti, Gustafsson, Mika, Lerm, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6557603/
https://www.ncbi.nlm.nih.gov/pubmed/31010371
http://dx.doi.org/10.1080/15592294.2019.1603963