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Hormone therapy use and breast tissue DNA methylation: analysis of epigenome wide data from the normal breast study

Hormone therapy (HT) is associated with increased risk of breast cancer, strongly dependent on type, duration, and recency of use. HT use could affect cancer risk by changing breast tissue transcriptional programs. We hypothesize that these changes are preceded by changes in DNA methylation. To expl...

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Detalles Bibliográficos
Autores principales: Harlid, Sophia, Xu, Zongli, Kirk, Erin, Wilson, Lauren E., Troester, Melissa A., Taylor, Jack A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6557608/
https://www.ncbi.nlm.nih.gov/pubmed/30821641
http://dx.doi.org/10.1080/15592294.2019.1580111