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The cyclophilin inhibitor CRV431 inhibits liver HBV DNA and HBsAg in transgenic mice
Hepatitis B virus (HBV) infection is a major health burden worldwide with 240 million chronically infected individuals. Nucleos(t)ide analogs and interferons are the current standards of care due to their suppression of HBV replication, but the treatments rarely eradicate HBV from individuals. Simil...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6557616/ https://www.ncbi.nlm.nih.gov/pubmed/31181107 http://dx.doi.org/10.1371/journal.pone.0217433 |