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Quantifying Retinal Pigment Epithelium Dysmorphia and Loss of Histologic Autofluorescence in Age-Related Macular Degeneration

PURPOSE: Lipofuscin and melanolipofuscin organelles in retinal pigment epithelium (RPE) cells are signal sources for clinical fundus autofluorescence (AF). To elucidate the subcellular basis of AF imaging, we identified, characterized, and quantified the frequency of RPE morphology and AF phenotypes...

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Detalles Bibliográficos
Autores principales: Gambril, J. Alan, Sloan, Kenneth R., Swain, Thomas A., Huisingh, Carrie, Zarubina, Anna V., Messinger, Jeffrey D., Ach, Thomas, Curcio, Christine A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6557619/
https://www.ncbi.nlm.nih.gov/pubmed/31173079
http://dx.doi.org/10.1167/iovs.19-26949