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Quantifying Retinal Pigment Epithelium Dysmorphia and Loss of Histologic Autofluorescence in Age-Related Macular Degeneration
PURPOSE: Lipofuscin and melanolipofuscin organelles in retinal pigment epithelium (RPE) cells are signal sources for clinical fundus autofluorescence (AF). To elucidate the subcellular basis of AF imaging, we identified, characterized, and quantified the frequency of RPE morphology and AF phenotypes...
Autores principales: | Gambril, J. Alan, Sloan, Kenneth R., Swain, Thomas A., Huisingh, Carrie, Zarubina, Anna V., Messinger, Jeffrey D., Ach, Thomas, Curcio, Christine A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Association for Research in Vision and Ophthalmology
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6557619/ https://www.ncbi.nlm.nih.gov/pubmed/31173079 http://dx.doi.org/10.1167/iovs.19-26949 |
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