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Type 1-programmed dendritic cells drive antigen-specific latency reversal and immune elimination of persistent HIV-1

BACKGROUND: Despite the success of antiretroviral therapy (ART), latent HIV-1 continues to persist in a long-lived population of resting memory CD4(+) T cells within those who are infected. Finding a safe and effective means to induce latency reversal (LR) during ART to specifically expose this late...

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Detalles Bibliográficos
Autores principales: Kristoff, Jan, Palma, Mariana L., Garcia-Bates, Tatiana M., Shen, Chengli, Sluis-Cremer, Nicolas, Gupta, Phalguni, Rinaldo, Charles R., Mailliard, Robbie B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6557749/
https://www.ncbi.nlm.nih.gov/pubmed/30952614
http://dx.doi.org/10.1016/j.ebiom.2019.03.077