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Postnatal N-acetylcysteine administration rescues impaired social behaviors and neurogenesis in Slc13a4 haploinsufficient mice
BACKGROUND: Sulfate availability is crucial for the sulfonation of brain extracellular matrix constituents, membrane phospholipids, neurosteroids, and neurotransmitters. Observations from humans and mouse models suggest dysregulated sulfate levels may be associated with neurodevelopmental disorders,...
Autores principales: | Zhang, Zhe, Dawson, Paul Anthony, Piper, Michael, Simmons, David Gordon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6557756/ https://www.ncbi.nlm.nih.gov/pubmed/30956169 http://dx.doi.org/10.1016/j.ebiom.2019.03.081 |
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