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A Multidimensional Characterization of E3 Ubiquitin Ligase and Substrate Interaction Network
E3 ubiquitin ligases (E3s) play a critical role in molecular and cellular mechanisms. However, a large number of E3-substrate interactions (ESIs) remain unrevealed. Here, we integrated the increasing omics data with biological knowledge to characterize and identify ESIs. Multidimensional features we...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6557761/ https://www.ncbi.nlm.nih.gov/pubmed/31181401 http://dx.doi.org/10.1016/j.isci.2019.05.033 |