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A Multidimensional Characterization of E3 Ubiquitin Ligase and Substrate Interaction Network

E3 ubiquitin ligases (E3s) play a critical role in molecular and cellular mechanisms. However, a large number of E3-substrate interactions (ESIs) remain unrevealed. Here, we integrated the increasing omics data with biological knowledge to characterize and identify ESIs. Multidimensional features we...

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Detalles Bibliográficos
Autores principales: Chen, Di, Liu, Xiaolong, Xia, Tian, Tekcham, Dinesh Singh, Wang, Wen, Chen, Huan, Li, Tongming, Lu, Chang, Ning, Zhen, Liu, Xiumei, Liu, Jing, Qi, Huan, He, Hui, Piao, Hai-long
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6557761/
https://www.ncbi.nlm.nih.gov/pubmed/31181401
http://dx.doi.org/10.1016/j.isci.2019.05.033