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Retrograde monosynaptic tracing through an engineered human embryonic stem cell line reveals synaptic inputs from host neurons to grafted cells

Retrograde monosynaptic tracing with EnvA-pseudotyped rabies virus has been employed to identify the afferent and efferent connectivity of transplanted human embryonic stem (hES) cell-derived neurons in animal models. Due to the protracted development of transplanted human neurons in host animals, i...

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Detalles Bibliográficos
Autores principales: Xing, Qi, Lin, Aiping, Su, Zhenghui, Liu, Chunhua, Huang, Wenhao, Guo, Wenjing, Pan, Guangjin, Guo, Yiping, Zhong, Xiaofen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chinese Society for Cell Biology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6557763/
https://www.ncbi.nlm.nih.gov/pubmed/31205682
http://dx.doi.org/10.1016/j.cr.2019.01.002