Beyond multidrug resistance: Leveraging rare variants with machine and statistical learning models in Mycobacterium tuberculosis resistance prediction

BACKGROUND: The diagnosis of multidrug resistant and extensively drug resistant tuberculosis is a global health priority. Whole genome sequencing of clinical Mycobacterium tuberculosis isolates promises to circumvent the long wait times and limited scope of conventional phenotypic antimicrobial susc...

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Detalles Bibliográficos
Autores principales: Chen, Michael L., Doddi, Akshith, Royer, Jimmy, Freschi, Luca, Schito, Marco, Ezewudo, Matthew, Kohane, Isaac S., Beam, Andrew, Farhat, Maha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Research paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6557804/
https://www.ncbi.nlm.nih.gov/pubmed/31047860
http://dx.doi.org/10.1016/j.ebiom.2019.04.016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6557804/
https://www.ncbi.nlm.nih.gov/pubmed/31047860
http://dx.doi.org/10.1016/j.ebiom.2019.04.016

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