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MiR-338-5p promotes metastasis of colorectal cancer by inhibition of phosphatidylinositol 3-kinase, catalytic subunit type 3-mediated autophagy pathway

BACKGROUND: In our preliminary screening, expression of miR-338-5p was found to be higher in primary colorectal cancer (CRC) with metastasis. The autophagy related gene- phosphatidylinositol 3-kinase, catalytic subunit type 3 (PIK3C3) appeared to be targeted by miR-338-5p. Here, we provide solid evi...

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Detalles Bibliográficos
Autores principales: Chu, Chien-An, Lee, Chung-Ta, Lee, Jenq-Chang, Wang, Yi-Wen, Huang, Ching-Tang, Lan, Sheng-Hui, Lin, Peng-Chan, Lin, Bo-Wen, Tian, Yu-Feng, Liu, Hsiao-Sheng, Chow, Nan-Haw
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6557806/
https://www.ncbi.nlm.nih.gov/pubmed/30982765
http://dx.doi.org/10.1016/j.ebiom.2019.04.010