Hepatitis C virus sequence divergence preserves p7 viroporin structural and dynamic features

The hepatitis C virus (HCV) viroporin p7 oligomerizes to form ion channels, which are required for the assembly and secretion of infectious viruses. The 63-amino acid p7 monomer has two putative transmembrane domains connected by a cytosolic loop, and has both N- and C- termini exposed to the endopl...

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Detalles Bibliográficos
Autores principales: Oestringer, Benjamin P., Bolivar, Juan H., Claridge, Jolyon K., Almanea, Latifah, Chipot, Chris, Dehez, François, Holzmann, Nicole, Schnell, Jason R., Zitzmann, Nicole
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6557816/
https://www.ncbi.nlm.nih.gov/pubmed/31182749
http://dx.doi.org/10.1038/s41598-019-44413-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6557816/
https://www.ncbi.nlm.nih.gov/pubmed/31182749
http://dx.doi.org/10.1038/s41598-019-44413-x

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