Whole-blood transcriptomic signatures induced during immunization by chloroquine prophylaxis and Plasmodium falciparum sporozoites

A highly effective vaccine that confers sterile protection to malaria is urgently needed. Immunization under chemoprophylaxis with sporozoites (CPS) consistently confers high levels of protection in the Controlled Human Malaria infection (CHMI) model. To provide a broad, unbiased assessment of the c...

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Detalles Bibliográficos
Autores principales: Tran, Tuan M., Bijker, Else M., Haks, Mariëlle C., Ottenhoff, Tom H. M., Visser, Leo, Schats, Remko, Venepally, Pratap, Lorenzi, Hernan, Crompton, Peter D., Sauerwein, Robert W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6557840/
https://www.ncbi.nlm.nih.gov/pubmed/31182757
http://dx.doi.org/10.1038/s41598-019-44924-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6557840/
https://www.ncbi.nlm.nih.gov/pubmed/31182757
http://dx.doi.org/10.1038/s41598-019-44924-7

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