Cargando…

Spaced training improves learning in Ts65Dn and Ube3a mouse models of intellectual disabilities

Benefits of distributed learning strategies have been extensively described in the human literature, but minimally investigated in intellectual disability syndromes. We tested the hypothesis that training trials spaced apart in time could improve learning in two distinct genetic mouse models of neur...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lauterborn, J. C., Schultz, M. N., Le, A. A., Amani, M., Friedman, A. E., Leach, P. T., Gall, C. M., Lynch, G. S., Crawley, J. N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6557858/ https://www.ncbi.nlm.nih.gov/pubmed/31182707 http://dx.doi.org/10.1038/s41398-019-0495-5

Ejemplares similares

Breathing and Oxygen Carrying Capacity in Ts65Dn and Down Syndrome
por: DeRuisseau, Lara R, et al.
Publicado: (2023)

Pathological trajectory in the Ts65Dn model of Down syndrome
por: Tallino, Savannah, et al.
Publicado: (2023)

Galantamine improves olfactory learning in the Ts65Dn mouse model of Down syndrome
por: Simoes de Souza, Fabio M., et al.
Publicado: (2011)

Cholinergic Senescence in the Ts65Dn Mouse Model for Down Syndrome
por: Kirstein, Martina, et al.
Publicado: (2022)

Increased male reproductive success in Ts65Dn “Down syndrome” mice
por: Moore, Clara S., et al.
Publicado: (2010)

Digastric Muscle Phenotypes of the Ts65Dn Mouse Model of Down Syndrome
por: Glass, Tiffany J., et al.
Publicado: (2016)

Synaptic Vesicle Recycling Is Unaffected in the Ts65Dn Mouse Model of Down Syndrome
por: Marland, Jamie R. K., et al.
Publicado: (2016)

Hypocellularity in the Murine Model for Down Syndrome Ts65Dn Is Not Affected by Adult Neurogenesis
por: López-Hidalgo, Rosa, et al.
Publicado: (2016)

Rescue of deficits by Brwd1 copy number restoration in the Ts65Dn mouse model of Down syndrome
por: Fulton, Sasha L., et al.
Publicado: (2022)

Luteolin induces hippocampal neurogenesis in the Ts65Dn mouse model of Down syndrome
por: Zhou, Wen-Bo, et al.
Publicado: (2019)

Identification of the translocation breakpoints in the Ts65Dn and Ts1Cje mouse lines: relevance for modeling down syndrome
por: Duchon, Arnaud, et al.
Publicado: (2011)

Protein Dynamics Associated with Failed and Rescued Learning in the Ts65Dn Mouse Model of Down Syndrome
por: Ahmed, Md. Mahiuddin, et al.
Publicado: (2015)

Spatiotemporal development of spinal neuronal and glial populations in the Ts65Dn mouse model of Down syndrome
por: Aziz, Nadine M., et al.
Publicado: (2019)

Deleterious Effects of Chronic Folate Deficiency in the Ts65Dn Mouse Model of Down Syndrome
por: Helm, Susan, et al.
Publicado: (2017)

The Adult Ts65Dn Mouse Model of Down Syndrome Shows Altered Swallow Function
por: Glass, Tiffany J., et al.
Publicado: (2019)

Glutamatergic synaptic deficits in the prefrontal cortex of the Ts65Dn mouse model for Down syndrome
por: Thomazeau, Aurore, et al.
Publicado: (2023)

Longitudinal neuroanatomical and behavioral analyses show phenotypic drift and variability in the Ts65Dn mouse model of Down syndrome
por: Shaw, Patricia R., et al.
Publicado: (2020)

Heart rate and blood pressure in male Ts65Dn mice: a model to investigate cardiovascular responses in Down syndrome
por: DeRuisseau, Lara R., et al.
Publicado: (2019)

Assessing Apoptosis Gene Expression Profiling with a PCR Array in the Hippocampus of Ts65Dn Mice
por: Yu, Bin, et al.
Publicado: (2015)

Altered intrinsic and network properties of neocortical neurons in the Ts65Dn mouse model of Down syndrome
por: Cramer, Nathan P., et al.
Publicado: (2015)

Phosphoproteomic Alterations of Ionotropic Glutamate Receptors in the Hippocampus of the Ts65Dn Mouse Model of Down Syndrome
por: Gómez de Salazar, Macarena, et al.
Publicado: (2018)

Signalling pathways contributing to learning and memory deficits in the Ts65Dn mouse model of Down syndrome
por: Freeburn, Aimée, et al.
Publicado: (2021)

Effects of Neonatal Neural Progenitor Cell Implantation on Adult Neuroanatomy and Cognition in the Ts65Dn Model of Down Syndrome
por: Rachubinski, Angela L., et al.
Publicado: (2012)

Involvement of Potassium and Cation Channels in Hippocampal Abnormalities of Embryonic Ts65Dn and Tc1 Trisomic Mice
por: Stern, Shani, et al.
Publicado: (2015)

Lifespan analysis of brain development, gene expression and behavioral phenotypes in the Ts1Cje, Ts65Dn and Dp(16)1/Yey mouse models of Down syndrome
por: Aziz, Nadine M., et al.
Publicado: (2018)

Evidence of Energy Metabolism Alterations in Cultured Neonatal Astrocytes Derived from the Ts65Dn Mouse Model of Down Syndrome
por: Zampieri, Bruna L., et al.
Publicado: (2022)

Increased excitability and altered action potential waveform in cerebellar granule neurons of the Ts65Dn mouse model of Down syndrome
por: Usowicz, Maria M., et al.
Publicado: (2012)

Bone Marrow Ts65Dn Trisomy-Induced Changes in Platelet Functionality and Lymphocytopenia Do Not Impact Atherosclerosis Susceptibility in Mice
por: Korporaal, Suzanne J. A., et al.
Publicado: (2021)

Monoacylglycerol Lipase Inhibitor JZL184 Improves Behavior and Neural Properties in Ts65Dn Mice, a Model of Down Syndrome
por: Lysenko, Larisa V., et al.
Publicado: (2014)

Re-establishment of the epigenetic state and rescue of kinome deregulation in Ts65Dn mice upon treatment with green tea extract and environmental enrichment
por: De Toma, I., et al.
Publicado: (2020)

Altered synaptic marker abundance in the hippocampal stratum oriens of Ts65Dn mice is associated with exuberant expression of versican
por: Howell, Matthew D, et al.
Publicado: (2012)

Rapamycin Treatment Ameliorates Age-Related Accumulation of Toxic Metabolic Intermediates in Brains of the Ts65Dn Mouse Model of Down Syndrome and Aging
por: Duval, Nathan, et al.
Publicado: (2018)

Emergence of Treadmill Running Ability and Quantitative Assessment of Gait Dynamics in Young Ts65Dn Mice: A Mouse Model for Down Syndrome
por: Scott-McKean, Jonah J., et al.
Publicado: (2023)

Pharmacological Modulation of Three Modalities of CA1 Hippocampal Long-Term Potentiation in the Ts65Dn Mouse Model of Down Syndrome
por: Scott-McKean, Jonah J., et al.
Publicado: (2018)

Inhibition of APP gamma-secretase restores Sonic Hedgehog signaling and neurogenesis in the Ts65Dn mouse model of Down syndrome
por: Giacomini, Andrea, et al.
Publicado: (2015)

Timing of Treatment with the Flavonoid 7,8-DHF Critically Impacts on Its Effects on Learning and Memory in the Ts65Dn Mouse
por: Giacomini, Andrea, et al.
Publicado: (2019)

Physical Training Chronically Stimulates the Motor Neuron Cell Nucleus in the Ts65Dn Mouse, a Model of Down Syndrome
por: Inguscio, Chiara Rita, et al.
Publicado: (2023)

Noninvasive assessment of autonomic modulation of heart rate variability in the Ts65Dn mouse model of Down syndrome: A proof of principle study
por: Roque, Adriano L., et al.
Publicado: (2020)

Long-term effect of neonatal inhibition of APP gamma-secretase on hippocampal development in the Ts65Dn mouse model of Down syndrome
por: Stagni, Fiorenza, et al.
Publicado: (2017)

Early neurotrophic pharmacotherapy rescues developmental delay and Alzheimer’s-like memory deficits in the Ts65Dn mouse model of Down syndrome
por: Kazim, Syed Faraz, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_7crtbmr6jmlkqhpjdvq7l90pif