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Enhanced avidity from a multivalent fluorescent antimicrobial peptide enables pathogen detection in a human lung model

Rapid in situ detection of pathogens coupled with high resolution imaging in the distal human lung has the potential to provide new insights and diagnostic utility in patients in whom pneumonia is suspected. We have previously described an antimicrobial peptide (AMP) Ubiquicidin (fragment UBI(29–41)...

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Detalles Bibliográficos
Autores principales: Akram, Ahsan R., Avlonitis, Nicolaos, Scholefield, Emma, Vendrell, Marc, McDonald, Neil, Aslam, Tashfeen, Craven, Thomas H., Gray, Calum, Collie, David S., Fisher, Andrew J., Corris, Paul A., Walsh, Timothy, Haslett, Christopher, Bradley, Mark, Dhaliwal, Kevin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6557859/
https://www.ncbi.nlm.nih.gov/pubmed/31182770
http://dx.doi.org/10.1038/s41598-019-44804-0