Cargando…

Genetic analyses of early-onset Alzheimer’s disease using next generation sequencing

Alzheimer’s disease (AD) is the most common type of neurodegenerative dementia, but the cause of AD remained poorly understood. Many mutations in the amyloid precursor protein (APP) and presenilin 1 and 2 (PSEN1 and PSEN2) have been reported as the pathogenic causes of early-onset AD (EOAD), which a...

Descripción completa

Detalles Bibliográficos
Autores principales: Giau, Vo Van, Bagyinszky, Eva, Yang, Young Soon, Youn, Young Chul, An, Seong Soo A., Kim, Sang Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6557896/
https://www.ncbi.nlm.nih.gov/pubmed/31182772
http://dx.doi.org/10.1038/s41598-019-44848-2