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Phenotypic screening of nonsteroidal anti-inflammatory drugs identified mefenamic acid as a drug for the treatment of schistosomiasis

BACKGROUND: Treatment and control of schistosomiasis, one of the most insidious and serious parasitic diseases, depend almost entirely on a single drug, praziquantel. Since the funding for drug development for poverty-associated diseases is very limited, drug repurposing is a promising strategy. In...

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Detalles Bibliográficos
Autores principales: Lago, Eloi M., Silva, Marcos P., Queiroz, Talita G., Mazloum, Susana F., Rodrigues, Vinícius C., Carnaúba, Paulo U., Pinto, Pedro L., Rocha, Jefferson A., Ferreira, Leonardo L.G., Andricopulo, Adriano D., de Moraes, Josué
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6557910/
https://www.ncbi.nlm.nih.gov/pubmed/31027918
http://dx.doi.org/10.1016/j.ebiom.2019.04.029