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Phenotypic screening of nonsteroidal anti-inflammatory drugs identified mefenamic acid as a drug for the treatment of schistosomiasis
BACKGROUND: Treatment and control of schistosomiasis, one of the most insidious and serious parasitic diseases, depend almost entirely on a single drug, praziquantel. Since the funding for drug development for poverty-associated diseases is very limited, drug repurposing is a promising strategy. In...
Autores principales: | Lago, Eloi M., Silva, Marcos P., Queiroz, Talita G., Mazloum, Susana F., Rodrigues, Vinícius C., Carnaúba, Paulo U., Pinto, Pedro L., Rocha, Jefferson A., Ferreira, Leonardo L.G., Andricopulo, Adriano D., de Moraes, Josué |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6557910/ https://www.ncbi.nlm.nih.gov/pubmed/31027918 http://dx.doi.org/10.1016/j.ebiom.2019.04.029 |
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