International genomic definition of pneumococcal lineages, to contextualise disease, antibiotic resistance and vaccine impact

BACKGROUND: Pneumococcal conjugate vaccines have reduced the incidence of invasive pneumococcal disease, caused by vaccine serotypes, but non-vaccine-serotypes remain a concern. We used whole genome sequencing to study pneumococcal serotype, antibiotic resistance and invasiveness, in the context of...

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Detalles Bibliográficos
Autores principales: Gladstone, Rebecca A., Lo, Stephanie W., Lees, John A., Croucher, Nicholas J., van Tonder, Andries J., Corander, Jukka, Page, Andrew J., Marttinen, Pekka, Bentley, Leon J., Ochoa, Theresa J., Ho, Pak Leung, du Plessis, Mignon, Cornick, Jennifer E., Kwambana-Adams, Brenda, Benisty, Rachel, Nzenze, Susan A., Madhi, Shabir A., Hawkins, Paulina A., Everett, Dean B., Antonio, Martin, Dagan, Ron, Klugman, Keith P., von Gottberg, Anne, McGee, Lesley, Breiman, Robert F., Bentley, Stephen D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Research paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6557916/
https://www.ncbi.nlm.nih.gov/pubmed/31003929
http://dx.doi.org/10.1016/j.ebiom.2019.04.021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6557916/
https://www.ncbi.nlm.nih.gov/pubmed/31003929
http://dx.doi.org/10.1016/j.ebiom.2019.04.021

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