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Chronic heavy drinking drives distinct transcriptional and epigenetic changes in splenic macrophages

BACKGROUND: Chronic heavy alcohol drinking (CHD) leads to significant organ damage, increased susceptibility to infections, and delayed wound healing. These adverse outcomes are believed to be mediated by alterations in the function of myeloid cells; however, the mechanisms underlying these changes...

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Detalles Bibliográficos
Autores principales: Sureshchandra, Suhas, Stull, Cara, Ligh, Brian Jin Kee, Nguyen, Selene Bich, Grant, Kathleen A., Messaoudi, Ilhem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6557917/
https://www.ncbi.nlm.nih.gov/pubmed/31005514
http://dx.doi.org/10.1016/j.ebiom.2019.04.027