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Chronic heavy drinking drives distinct transcriptional and epigenetic changes in splenic macrophages
BACKGROUND: Chronic heavy alcohol drinking (CHD) leads to significant organ damage, increased susceptibility to infections, and delayed wound healing. These adverse outcomes are believed to be mediated by alterations in the function of myeloid cells; however, the mechanisms underlying these changes...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6557917/ https://www.ncbi.nlm.nih.gov/pubmed/31005514 http://dx.doi.org/10.1016/j.ebiom.2019.04.027 |