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Immunomodulation in Primary Immune Thrombocytopenia: A Possible Role of the Fc Fragment of Romiplostim?

Fc fusion proteins and Fc fusion peptides or peptibodies are chimeric molecules composed of an active pharmacological protein or peptide and the Fc fragment of an immunoglobulin. The primary aim of this drug construct is to prolong the half-life of the active component. This molecular architecture i...

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Detalles Bibliográficos
Autores principales: Schifferli, Alexandra, Nimmerjahn, Falk, Kühne, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6557984/
https://www.ncbi.nlm.nih.gov/pubmed/31214173
http://dx.doi.org/10.3389/fimmu.2019.01196