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The Transcriptional Landscape of Microglial Genes in Aging and Neurodegenerative Disease
Microglia, the brain-resident myeloid cells, are strongly implicated in Alzheimer's disease (AD) pathogenesis by human genetics. However, the mechanisms by which microglial gene expression is regulated in a region-specific manner over the course of normal aging and in neurodegenerative disease...
Autores principales: | Bonham, Luke W., Sirkis, Daniel W., Yokoyama, Jennifer S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6557985/ https://www.ncbi.nlm.nih.gov/pubmed/31214167 http://dx.doi.org/10.3389/fimmu.2019.01170 |
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