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A PDGFRβ-based score predicts significant liver fibrosis in patients with chronic alcohol abuse, NAFLD and viral liver disease

BACKGROUND: Platelet Derived Growth Factor Receptor beta (PDGFRβ) has been associated to hepatic stellate cell activation and has been the target of multiple therapeutic studies. However, little is known concerning its use as a diagnostic agent. METHODS: Circulating PDGFRβ levels were analysed in a...

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Detalles Bibliográficos
Autores principales: Lambrecht, Joeri, Verhulst, Stefaan, Mannaerts, Inge, Sowa, Jan-Peter, Best, Jan, Canbay, Ali, Reynaert, Hendrik, van Grunsven, Leo A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6558023/
https://www.ncbi.nlm.nih.gov/pubmed/31036530
http://dx.doi.org/10.1016/j.ebiom.2019.04.036