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Factors Affecting Combination Trial Success (FACTS): Investigator Survey Results on Early-Phase Combination Trials

Experimental therapeutic oncology agents are often combined to circumvent tumor resistance to individual agents. However, most combination trials fail to demonstrate sufficient safety and efficacy to advance to a later phase. This study collected survey data on phase 1 combination therapy trials ide...

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Detalles Bibliográficos
Autores principales: Paller, Channing J., Huang, Erich P., Luechtefeld, Thomas, Massett, Holly A., Williams, Christopher C., Zhao, Jinxiu, Gravell, Amy E., Tamashiro, Tami, Reeves, Steven A., Rosner, Gary L., Carducci, Michael A., Rubinstein, Lawrence, Ivy, S. Percy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6558040/
https://www.ncbi.nlm.nih.gov/pubmed/31214592
http://dx.doi.org/10.3389/fmed.2019.00122