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Discovery of Potential Anti-infective Therapy Targeting Glutamine Synthetase in Staphylococcus xylosus

Glutamine synthetase (GS), which catalyzes the production of glutamine, plays essential roles in most biological growth and biofilm formation, suggesting that GS may be used as a promising target for antibacterial therapy. We asked whether a GS inhibitor could be found as an anti-infective agent of...

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Detalles Bibliográficos
Autores principales: Cui, Wen-Qiang, Qu, Qian-Wei, Wang, Jin-Peng, Bai, Jing-Wen, Bello-Onaghise, God'spower, Li, Yu-Ang, Zhou, Yong-Hui, Chen, Xing-Ru, Liu, Xin, Zheng, Si-Di, Xing, Xiao-Xu, Eliphaz, Nsabimana, Li, Yan-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6558069/
https://www.ncbi.nlm.nih.gov/pubmed/31214565
http://dx.doi.org/10.3389/fchem.2019.00381