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Brpf1 Haploinsufficiency Impairs Dendritic Arborization and Spine Formation, Leading to Cognitive Deficits

Haploinsufficiency of the bromodomain and PHD finger-containing protein 1 (BRPF1) gene causes intellectual disability (ID), which is characterized by impaired intellectual and cognitive function; however, the neurological basis for ID and the neurological function of BRPF1 dosage in the brain remain...

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Detalles Bibliográficos
Autores principales: Su, Yan, Liu, Junhua, Yu, Baocong, Ba, Ru, Zhao, Chunjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6558182/
https://www.ncbi.nlm.nih.gov/pubmed/31213987
http://dx.doi.org/10.3389/fncel.2019.00249