Unveiling the Diversity of Immunoglobulin Heavy Constant Gamma (IGHG) Gene Segments in Brazilian Populations Reveals 28 Novel Alleles and Evidence of Gene Conversion and Natural Selection

Even though immunoglobulins are critical for immune responses and human survival, the diversity of the immunoglobulin heavy chain gene (IGH) is poorly known and mostly characterized only by serological methods. Moreover, this genomic region is not well-covered in genomic databases and genome-wide as...

Descripción completa

Detalles Bibliográficos
Autores principales: Calonga-Solís, Verónica, Malheiros, Danielle, Beltrame, Marcia Holsbach, Vargas, Luciana de Brito, Dourado, Renata Montoro, Issler, Hellen Caroline, Wassem, Roseli, Petzl-Erler, Maria Luiza, Augusto, Danillo G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6558194/
https://www.ncbi.nlm.nih.gov/pubmed/31214166
http://dx.doi.org/10.3389/fimmu.2019.01161

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6558194/
https://www.ncbi.nlm.nih.gov/pubmed/31214166
http://dx.doi.org/10.3389/fimmu.2019.01161

Ejemplares similares