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Signal Integration of IFN-I and IFN-II With TLR4 Involves Sequential Recruitment of STAT1-Complexes and NFκB to Enhance Pro-inflammatory Transcription

Atherosclerosis is a chronic inflammatory disease of the blood vessels, characterized by atherosclerotic lesion formation. Vascular Smooth Muscle Cells (VSMC), macrophages (MΦ), and dendritic cells (DC) play a crucial role in vascular inflammation and atherosclerosis. Interferon (IFN)α, IFNγ, and To...

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Detalles Bibliográficos
Autores principales: Piaszyk-Borychowska, Anna, Széles, Lajos, Csermely, Attila, Chiang, Hsin-Chien, Wesoły, Joanna, Lee, Chien-Kuo, Nagy, Laszlo, Bluyssen, Hans A. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6558219/
https://www.ncbi.nlm.nih.gov/pubmed/31231385
http://dx.doi.org/10.3389/fimmu.2019.01253