Laboratory Evolution Assays and Whole-Genome Sequencing for the Development and Safety Evaluation of Lactobacillus plantarum With Stable Resistance to Gentamicin

The goal of this work was to use laboratory evolution assays and whole-genome sequencing to develop and test the safety of a probiotic, Lactobacillus plantarum, with high-level of resistance to gentamicin. The evolution of L. plantarum was evaluated under the selective pressure from gentamicin and s...

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Detalles Bibliográficos
Autores principales: Dong, Yushan, Zhang, Fuxin, Wang, Bini, Gao, Jiayuan, Zhang, Jiangtao, Shao, Yuyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6558246/
https://www.ncbi.nlm.nih.gov/pubmed/31231332
http://dx.doi.org/10.3389/fmicb.2019.01235

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6558246/
https://www.ncbi.nlm.nih.gov/pubmed/31231332
http://dx.doi.org/10.3389/fmicb.2019.01235

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